I think you should stop taking the Lsine. It is definitely causing your skin to be more oily/healthy hence the breakouts. I went through accutane treatment for severe acne. my skin has been completely clear since treatment and it has been almost 2 years. I started taking lsine 1000 MG a day and it started causing me to breakout on my face too. All of a sudden unexpectedly. I stopped taking it for just 2 weeks and my skin cleared back up completely. I would advise taking acyclovir prescription medication when you feel a fever blister coming on and it will get rid of it overnight. works for me everytime. sometimes it will take 2-3 days to heal completely. this is the only thing that works. lsine may help prevent fever blisters but it also is causing me to breakout on my face, so I am no longer taking it. I would advise you to stay away from the lysine for now. hope that helps!

I am glad I found this thread. I see it's been awhile since you've posted this thread so I don't know if you'll see this.

I started taking l-Lysine because of its claim to control cold sores. It definatly suppressed them, but other issues occurred so I have discontinued the supplement and am using Valtrex as suppression therapy instead.

Just like you, I went from having clear skin (except for hormonal breakouts from time to time) to buying every acne face wash and treatment I could find. It felt like I woke up every day with 1-2 more spots forming. It was very frustrating. I didn't put the pieces together until I got a breakthrough cold sore and I started researching the supplement more thoroughly. I read about claims of it clearing up skin problems, which led me to think that I had the adverse reaction. I discontinued l-Lysine about 3 weeks ago and I see an immediate change. Who knew this could happen? I guess I learned something though. I will be researching vitamins and supplements more carefully before I start anything new again.

I'm happy we figured it out!

I'm getting off of my L-lysine regimen. My acne has returned with a vengeance and I have a new one or two lesions every day. I had been on Accutane back in my 20s, it got rid of all of my acne and now this with the L-lysine due to HSV-2 being the reason I began taking L-lysine and although I have to say it does clear the out breaks of Herpes, it also enrages my acne. I can't and won't take it anymore.

Read online about Silver gel and I totally forgot that I've taken the liquid form in the past with good results. Now will add the gel topically when an outbreak begins to form. Also will continue with coconut oil both internally and externally and castor oil used topically only. The castor seems to suffocate the virus almost immediately when applied topically while also soothing the skin.

Hope this post helps if anyone is having similar issues.

I was recently diagnosed with my first lip cold sore. I had read that lysine was a great supplement to take to speed up the healing process, as well as prevention. I was on Valtrex and two days later I started lysine supplement, taking 3000 mg a day. After a few days, my face started feeling warm and a few days after that I started getting bumps on my skin. I thought cold sores spread to my upper lip, but then it started spreading all over my face. I have since ceased the lysine supplements, going on 4 days now. Im not sure if that was the cause or if the cold sore had spread across my face.

I had researched lysine, and I found this forum stating the negative affects it had on people. Ive attached a photo to see if this looks at all familiar with your experience.

had to wait a few days but Im going to be seeing my dermatologist. Saw my GP and he wasnt sure what the issue is but gave me antibiotics hoping that would help.

I know this is an old thread, but hopefully someone sees it.

@deedle7769 I believe that L-lysine was the cause of your breakouts because I took it too and my face broke out within a few days. I was prescribed the antibiotic Doxycycline and it took over like a 6 month period to see a difference in my case. I hope yours clears up soon.

Wow, yeah, yours looks similar to mine. My dermatologist thought I had a rosacea type 2 break out (which Ive had happen like 4 years ago). I had asked about the Lysine, but he didnt know much about it. My doctor put me on the same antibiotic, but I didnt feel comfortable taking it long-term. So I discontinued that after a week and looked into topicals. I read that anzelaic acid could help. I got a 20% topical and it worked wonders to heal the bumps and scars. Everything is pretty much gone, except for a few pigmented scars.

@deedle7769 Oh wow, my dermatologist also believed it was also rosacea related so that is interesting. Im glad to hear that the azelaic is working for you and taking probiotics/prebiotic foods should help inflammation on the inside as well!