Hi, yes it certainly can but not usually more than 5-15 lbs. From what I understand, estrogen = more fat cells so lowering male hormones, which is what Spiro does, raises the effects of estrogen. I'm oversimplifying but... The good news is its generally in your butt and boobs. I'm having breast tenderness.
i think of you continue to eat healthy and exercise you will have no or minimal weight gain.
I know it's not ideal but Ill take s few extra pounds and clear skin over acne any day.
Some people have no weight gain. Like birth control its all pretty much how each person reacts to the med.