Chemical Peels

Chemical Exfoliation
Compare To Other Treatments

Pregnancy

There are no adequate and well-controlled studies on the use of topical salicylic acid in pregnant women. Animal studies showed that oral (not topical) administration of salicylic acid is teratogenic in rats and monkeys. However, it is difficult to extrapolate from oral doses used in these studies to human topical administration of salicylic acid. Thus, salicylic acid should be used during pregnancy only if the potential benefit justifies the risk to the fetus.

Glycolic acid and lactic acid are likely safe, with limited dermal penetration, but studies are lacking. 

There is little to no evidence about the safety of Jessner’s solution in pregnancy, however, since it contains salicylic acid, it should be considered with caution during pregnancy.

Little to no evidence is available on the safety of mandelic acid, citric acid, trichloracetic acid, lactic acid, polyhydroxy acid, amino fruit acid, and pyruvic acid in pregnancy.

Be sure to talk to your doctor before using chemical peels when pregnant or planning to become pregnant.

Breastfeeding

The excretion of chemical peels after topical treatment into human milk is unknown. There is not enough information on the safety of chemical peels during breastfeeding.

Consult your doctor regarding whether it is safe for you to get chemical peels during breastfeeding.

References
  1. Aad.org. (2024). Chemical peels. [online] Available at: https://www.aad.org/public/diseases/cosmetic-treatments/chemical-peels#overview. [Accessed 25 Sept. 2025].
  2. Castillo, D. E. & Keri, J. Chemical peels in the treatment of acne: patient selection and perspectives. Clinical, Cosmetic and Investigational Dermatology Volume 11, 365–372 (2018).
  3. Aad.org. (2024). Treatment of acne in the pregnant patient. [online] Available at: https://www.aad.org/faculty/handout/AM2018/accepted/FRM%20F116%20-%20Keri%20-%2013782%2010845.pdf. [Accessed 25 Sept. 2025].
  4. Cleveland Clinic (2024). Chemical Peels. [online] Available at: https://my.clevelandclinic.org/health/treatments/11010-chemical-peels [Accessed 25. Sept. 2024]