Oral Antibiotic
Reviews
3.2
1953 Reviews
Oral Antibiotic
Efficacy
54%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Note: Should never be used on its own and for a maximum of 3 months.
Oral Antibiotic
Side Effects
High
Oral Antibiotic
Acne.org’s Real World Take
Antibiotics should be used for a maximum of 3 months, provide only moderate benefit and only to some people, and may lead to side effects and strains of resistant bacteria. Studies do show they can reduce severe acne in the short term, but approach with caution and stay your own advocate.
Oral Antibiotic
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Minocycline
Compare To Other Treatments
5
17.3%
4
27.7%
3
24%
2
16%
1
14.9%

Used Minocycline? Rate It:

Choose from 1 to 5 stars
May 4, 2010

Pros:

It worked very well when you take it consistently

Cons:

stopped working completely once i stopped taking it

Well, I have very bad acne. When I got on Minocycline, it saved my teen years. However, I realized that being on this medication for 4 years and if i continue, can damage my liver and develop health issues. So when i stopped taking it, i broke out again like crazy. So basically, your skin is relying on this medication. I mean, having clear skin and under control is what I dreamed for, but replying on a oral medication is not worth it. My skin is bad again, but im just trying other options and wouldnt want to turn back to antibiotics to cure my acne.
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July 14, 2015
DO YOURSELF A FAVOR
I am 20 years old and started experiencing mild to severe cystic acne about a year ago. I've had cases where my blemishes have been the size of a nickel. My acne irritated my skin so much and I am now left with a lot of scarring. I have used many over the counter products, including Murad. I have spent hours researching the internet for remedies hoping for a solution. I finally decided to go to the dermatologist. Best choice I have made towards improving my skin. My doctor prescribed me with 100 mg two times a day with two other prescribed applicants. I truly believe acne needs to be cured from the inside out, along with a healthy diet and good exercise. I've only been on this medication for 2 weeks and I have seen such a dramatic difference. I am finally starting to gain my confidence, I am so excited to see what my complete outcome will be.
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February 17, 2012

Pros:

-Cleared cystic pimples, whiteheads
-Made skin less oily

Cons:

-Acne came back 2 months after stopping
-HORRIBLE stomach/GI side effects!
(nausea, diarrhea, vomiting, Gastritis, Esophagitis, awful cramping, heartburn, acid reflux) even after stopping Minocycline

I had acne from taking the pill, so my Derm prescribed this. It cleared up most of my acne quickly, so I stopped for 2 weeks after a month, but started up again when my acne came back. My skin was great the whole time I was on Mino, but I was constantly nauseous, sick, and dizzy. I was able to stop after 3 months and my skin stayed clear for about 2 months, before slowly getting about as bad as it was before, plus a TON of blackheads that I never had before. Even after I stopped taking it, the nausea continued and became so extreme that I ended up in all sorts of doctor's offices and had surgery before being diagnosed with Gastritis and Esophagitis from this pill. It's been over a year since I first took Mino, and I'm STILL dealing with the side effects. I was pretty healthy before this pill and spent weeks at a time completely bedridden because of the side effects and may possibly have gotten Crohn's Disease, which is a life long condition. I am 20 and unable to work because my flare ups are so severe and unpredictable. If you're going to take this pill, despite the huge correlation between Mino and Gastritis and Esophagitis, for the love of GOD, take it on a full stomach and don't take it before lying down (causes more acid erosion/heartburn and nausea) and take a probiotic every day to counteract the good bacteria that's being killed. Maybe you'll be lucky and will only experience minor nausea, but maybe THIS will happen (like it has for many) and you won't realize it until it's too late. If you start feeling sick, just stop the pill. I swear to you, it's not worth it. All of this, and my acne just came back. Please, just look at the side effects I posted and rethink it. It's like 24/7 morning sickness for a year and counting and there's nothing you can do about it. I wish I never took this pill.
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July 30, 2010

Pros:

Only had one giant spot whilst taking it

Cons:

Still had smaller spots
Felt out of it all the time - like I was watching my life on tv
Upset stomach
Constant thrush
Decreased appetite
Hyper-pigmentation (SP)

The drug definately reduced the size of spots but did not stop them completley. Took about 6 weeks to start seeing results taking 100mg a day. I think if I had continued to take it I would have seen improvements but the side effects were just too much and I would have wasted away! May work for some but now I am trying accutane as even though the side effects may be dire, there is more chance of long term improvement.
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June 29, 2011

Pros:

Clears up acne including cysts fairly quickly.

Cons:

Acne comes back once you stop. Doesn't do much for me when it comes to body acne.

While on minocycline my acne clears up 95%, having only small pimples that last a day or two. It does a great job of getting rid of the terrible cysts I get around my mouth/jawline. It keeps me clear for a few months but acne does return; though not nearly as bad as it was before. Unfortunately it hasn't done much for me when it comes to body acne.
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March 25, 2010

Pros:

- works amazingly.
- for me, personally, i do not have any of the ' first few day side affects. '
- ive only been on it for 2 days, and taken 2 pills off 100mg, but ive seen such a difference

Cons:

- the side affects i read that could happen are scary, but it is said that minocycline has the least amount of side affects, so i guess all oral pills have them.
- you are constantly thirsty.

i love it. for me , its was expensive. however, it has been working perfectly in just 2 days ! my old pimples are disappearing, and the small pimples that were hiding behind my skin are now coming out, and also going away. however, the reason that so many people get dizzy when taking this pill is because the pill absorbs water. YOU NEED TO HAVE EXTRA WATER ! you will not get dizzy. i think that you should also go back & check up with your doctor/ dermatologist every few weeks, so he/she can either lower or raise your daily amount. if you take to much. side affects will happen. if you take to little, there will be no results !
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January 4, 2010

Pros:

Cheap, I suppose. Cleared my acne a little.

Cons:

Gave me a comparatively rare and debilitating disease.

I went on this medication 3 years ago, and it gave me Pseudo Tumor Cerebri, which means my body produced too much spinal and cranial fluid. I went partially blind temporarily, suffered extreme headaches, and dizziness to the extent that I could not walk. I would rather walk around with worse acne than I had than have to repeat all of those medical visits where nobody knew what I had, and where I had to have repeated spinal taps. My advice is: no matter what medicine you take, become acquainted with ALL of the side effects - even rare ones. Then decide if you think the risk is worth it. I, personally, do not.
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January 3, 2011

Pros:

Helped decrease acne on my face and back after I'd been taking it for about 1month

Cons:

I had SEVERE vision problems while taking this. After about 2months of taking this I started to have really bad throbbing headaches with neck pain, I couldn't focus my eyes, adjust to light changes and had bright colorful blotches and lines across my vision even w/ eyes closed. My peripheral vision also decreased a lot. After I stopped taking these my vision started to get better right away but 3months later and my sight is still not 100% back to normal :(

I thought it worked pretty good before it started to make me go blind. With my insurance it cost about 10 bucks I think, but my overall Dr. bill for figuring out what was wrong with me is over $1,600 (with more visits scheduled for the near future) my optic nerve is still off the charts inflamed and I still have neck pain and decreased peripheral vision.....so i guess if you want to risk it go for it but I'd really recommend that if you try it that you keep track of how you feel on a day to day basis so you can consult your dr. with any health problems. Mine weren't sudden but gradually got worse over the period of about a month before I went to the Dr.
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October 12, 2010

Pros:

Cleared up SOME acne.

Cons:

Left me with greenish-blue bruises that haven't gone away for months, (I found out recently that this is due to the high concentration of the drug in my body, and have since stopped taking it)

Take it if you wish, but be really, really careful. If you notice anything odd at all, go to the doctor. (And ask if it could be from the drug, I actually went to the doctor specifically for the bruises, and the doctor had no clue what was wrong, and sent me for some blood tests that came back normal. A few days ago I found out that the bruising was from the minocycline via a 3 second Google search...*fail*)
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September 27, 2016
Works… then stops
I have to give this 2 stars because in all honesty, when I started taking it, I thought I had found a miracle drug. I was extremely hesitant to take prescription medication for my acne because we have all heard the horror stories. But after doing some research, I thought that this wouldn't be nearly as bad as, let's say, accutane. And I was pretty desperate because nothing else had been working. I obviously went through all the drug store brands, then moved onto some of the fancier stuff you find at Macy's - Jan Marini (WHOA expensive), MD complete and then moved onto other stuff like Proactive (I had to at least say I had tried it!!) and Exposed. At the end of the day, nothing worked for me. Not even a little. I would say if anything, most of the products caused my breakouts to get worse. Worse cysts that lasted longer, were bigger. It was pretty depressing. When those didn't work, t modified my diet which was extremely difficult for me to do. Getting rid of dairy and wheat was like total hell for me and at the end of the day, I didn't feel any better physically and my acne didn't improve. I felt like my moods were worse just from being bitter, and it ended up affecting my home life as well. My husband told me it was like walking on eggshells around me, which is tough to hear. I finally went to a dermatologist at the urging of my daughter who could see how much my skin was affecting me. They prescribed me minocycline and literally, after having tried so many other things, I finally felt relief. I immediately noticed a clearing for the first time in'10 years. I told everyone I could about how great it was. I was like pimping it!! Then within about a month, I started seeing the side effects. Like everyone else has said here, the headaches were unbearable and I am no stranger to headaches. No type of amount of medicine brought relief. My headaches would go in spurts so I did continue to use the minocycline for a while until I realized that it had actually stopped working as well. So now I was left with headaches and acne. So I stopped and the side effects ended almost immediately. I have come to find out that the problem with oral antibiotics is that they do in fact work - the bacteria they kill off are a part of what causes acne but not the entire cause. Once your body becomes used to the antibiotics, they cease to work because your bacteria is immune. Great! And your acne comes back with a vengeance as it did with me. Lucky for me, I got off of them - and I will never go back. And I have found a product that works for my skin better than anything else I have tried. Topical is the way to go!! Someone here mentioned a company called Ninja Skincare, I called and they put me on a treatment which has been my new miracle but with no side effects! and not a million bucks either. And it has been like 6 months of clear skin. And did I mention no more headaches?! So I am the happy ending to these stories. I hope everyone has a happy ending like mine. But I would never recommend this product. Or really any prescribed medication from everything I have read. There is no good that can come out of it and your acne never truly goes away. Stay topical my friends!
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Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.